HIV Target gene Detail Information

> PARP6 Gene Search Result

Gene Information

Gene Name	PARP6
Gene ID	56965
Gene Full Name	poly(ADP-ribose) polymerase family member 6
Gene Alias	ARTD17; pART17; PARP-6-C; PARP-6-B1
Transcripts	ENSG00000137817
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q2NL67
HGNC ID	HGNC:26921
VEGA ID	OTTHUMG00000133443
String ID	9606.ENSP00000456348
PharmGKB ID	PA134900863

Target gene [PARP6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013092	chr15	2	2		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PARP6 expression and immune infiltrating cell level correlation result in HIV+ samples
PARP6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PARP6 expression and immune infiltrating cell level correlation result in HIV+ samples
PARP6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).