HIV Target gene Detail Information

> PARP11 Gene Search Result

Gene Information

Gene Name	PARP11
Gene ID	57097
Gene Full Name	poly(ADP-ribose) polymerase family member 11
Gene Alias	ARTD11; MIB006; C12orf6
Transcripts	ENSG00000111224
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9NR21
HGNC ID	HGNC:1186
VEGA ID	OTTHUMG00000156442
OMIM ID	616706
String ID	9606.ENSP00000228820
PharmGKB ID	PA25507

Target gene [PARP11] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007837	chr12	15	2		17	View
4009710	chr12	8	3		11	View
4011040	chr12	3	4		7	View
4015022	chr12	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PARP11 expression and immune infiltrating cell level correlation result in HIV+ samples
PARP11 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PARP11 expression and immune infiltrating cell level correlation result in HIV+ samples
PARP11 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).