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HBV Target gene Detail Information

> PARD3 Gene Search Result


Gene Information
Gene Name PARD3
Gene ID 56288
Gene Full Name par-3 family cell polarity regulator
Gene Alias Baz; ASIP; PAR3; PARD-3; PARD3A; SE2-5T2; PPP1R118; SE2-5L16; SE2-5LT1; PAR3alpha
Transcripts ENSG00000148498
Virus HBV
Gene Type protein coding
HPA Location Info Cell Junctions;Plasma membrane;
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q8TEW0
HGNC ID HGNC:16051
VEGA ID OTTHUMG00000017948
OMIM ID 606745
String ID 9606.ENSP00000363921
PharmGKB ID PA32936
Target gene [PARD3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002463 chr10 57 42 170 269 View
1002593 chr10 55 37 149 241 View
1006806 chr10 10 24 34 View
1009846 chr10 7 7 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of PARD3 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
PARD3 expression: Low -> High
Lollipop of PARD3 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of PARD3 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PARD3 expression and immune infiltrating cell level correlation result in HBV+ samples
PARD3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).