HIV Target gene Detail Information

> PAQR4 Gene Search Result

Gene Information

Gene Name	PAQR4
Gene ID	124222
Gene Full Name	progestin and adipoQ receptor family member 4
Transcripts	ENSG00000162073
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q8N4S7
HGNC ID	HGNC:26386
VEGA ID	OTTHUMG00000128977
OMIM ID	614578
String ID	9606.ENSP00000321804
PharmGKB ID	PA134945614

Target gene [PAQR4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004401	chr16	29	16		45	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PAQR4 expression and immune infiltrating cell level correlation result in HIV+ samples
PAQR4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PAQR4 expression and immune infiltrating cell level correlation result in HIV+ samples
PAQR4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).