HBV Target gene Detail Information

> PAPLN Gene Search Result

Gene Information

Gene Name	PAPLN
Gene ID	89932
Gene Full Name	papilin, proteoglycan like sulfated glycoprotein
Gene Alias	PPN
Transcripts	ENSG00000100767
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Predicted to be secreted;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	O95428
HGNC ID	HGNC:19262
VEGA ID	OTTHUMG00000171366
OMIM ID	617785
String ID	9606.ENSP00000345395
PharmGKB ID	PA134914395

Target gene [PAPLN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004782	chr14	24	19	26	69	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PAPLN expression and immune infiltrating cell level correlation result in HBV+ samples
PAPLN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).