HIV Target gene Detail Information

> PANK2 Gene Search Result

Gene Information

Gene Name	PANK2
Gene ID	80025
Gene Full Name	pantothenate kinase 2
Gene Alias	HSS; HARP; PKAN; NBIA1; C20orf48
Transcripts	ENSG00000125779
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q9BZ23
HGNC ID	HGNC:15894
VEGA ID	OTTHUMG00000031768
OMIM ID	606157
String ID	9606.ENSP00000313377
PharmGKB ID	PA38048

Target gene [PANK2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004641	chr20	30	11		41	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PANK2 expression and immune infiltrating cell level correlation result in HIV+ samples
PANK2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PANK2 expression and immune infiltrating cell level correlation result in HIV+ samples
PANK2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).