HIV Target gene Detail Information

> PAN2 Gene Search Result

Gene Information

Gene Name	PAN2
Gene ID	9924
Gene Full Name	poly(A) specific ribonuclease subunit PAN2
Gene Alias	USP52
Transcripts	ENSG00000135473
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q504Q3
HGNC ID	HGNC:20074
VEGA ID	OTTHUMG00000170412
OMIM ID	617447
String ID	9606.ENSP00000401721
PharmGKB ID	PA162398664

Target gene [PAN2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007315	chr12	13	7		20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PAN2 expression and immune infiltrating cell level correlation result in HIV+ samples
PAN2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PAN2 expression and immune infiltrating cell level correlation result in HIV+ samples
PAN2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).