HIV Target gene Detail Information

> PAG1 Gene Search Result

Gene Information

Gene Name	PAG1
Gene ID	55824
Gene Full Name	phosphoprotein membrane anchor with glycosphingolipid microdomains 1
Gene Alias	CBP; PAG
Transcripts	ENSG00000076641
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NWQ8
HGNC ID	HGNC:30043
VEGA ID	OTTHUMG00000164592
OMIM ID	605767
String ID	9606.ENSP00000220597
PharmGKB ID	PA142671201

Target gene [PAG1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002249	chr8	26	75	2	103	View
4002353	chr8	16	33	49	98	View
4008096	chr8	7	1	8	16	View
4008630	chr8		14		14	View
4010886	chr8		8		8	View
4012516	chr8		5		5	View
4012779	chr8	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PAG1 expression and immune infiltrating cell level correlation result in HIV+ samples
PAG1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PAG1 expression and immune infiltrating cell level correlation result in HIV+ samples
PAG1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).