HIV Target gene Detail Information

> PAF1 Gene Search Result

Gene Information

Gene Name	PAF1
Gene ID	54623
Gene Full Name	PAF1 homolog, Paf1/RNA polymerase II complex component
Gene Alias	PD2; F23149_1
Transcripts	ENSG00000006712
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8N7H5
HGNC ID	HGNC:25459
VEGA ID	OTTHUMG00000182968
OMIM ID	610506
String ID	9606.ENSP00000221265
PharmGKB ID	PA142671206

Target gene [PAF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003880	chr12	53			53	View
4004404	chr19	42	3		45	View
4006808	chr1	18	3	1	22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PAF1 expression and immune infiltrating cell level correlation result in HIV+ samples
PAF1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PAF1 expression and immune infiltrating cell level correlation result in HIV+ samples
PAF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).