HTLV1 Target gene Detail Information

> PADI3 Gene Search Result

Gene Information

Gene Name	PADI3
Gene ID	51702
Gene Full Name	peptidyl arginine deiminase 3
Gene Alias	PAD3; PDI3; UHS1
Transcripts	ENSG00000280549
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Vesicles;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q9ULW8
HGNC ID	HGNC:18337
VEGA ID	OTTHUMG00000002373
OMIM ID	606755
String ID	9606.ENSP00000364609
Drugbank ID	BE0002315
PharmGKB ID	PA32901

Target gene [PADI3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001841	chr1	310	13	12	335	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PADI3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PADI3 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PADI3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PADI3 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of PADI3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PADI3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).