HIV Target gene Detail Information

> PABPC1L Gene Search Result

Gene Information

Gene Name	PABPC1L
Gene ID	80336
Gene Full Name	poly(A) binding protein cytoplasmic 1 like
Gene Alias	EPAB; PABPC1L1; C20orf119; dJ1069P2.3
Transcripts	ENSG00000101104
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nuclear bodies;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q4VXU2
HGNC ID	HGNC:15797
VEGA ID	OTTHUMG00000032553
String ID	9606.ENSP00000255136
PharmGKB ID	PA162398552

Target gene [PABPC1L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002146	chr20	94	17		111	View
4002147	chr20	94	17		111	View
4002904	chr20	62	14		76	View
4002905	chr20	62	14		76	View
4002906	chr20	62	14		76	View
4002907	chr20	62	14		76	View
4002908	chr20	62	14		76	View
4002909	chr20	62	14		76	View
4002959	chr20	62	12		74	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PABPC1L expression and immune infiltrating cell level correlation result in HIV+ samples
PABPC1L expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PABPC1L expression and immune infiltrating cell level correlation result in HIV+ samples
PABPC1L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).