HBV Target gene Detail Information

> PABPC1 Gene Search Result

Gene Information

Gene Name	PABPC1
Gene ID	26986
Gene Full Name	poly(A) binding protein cytoplasmic 1
Gene Alias	PAB1; PABP; PABP1; PABPC2; PABPL1
Transcripts	ENSG00000070756
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P11940
HGNC ID	HGNC:8554
VEGA ID	OTTHUMG00000164779
OMIM ID	604679
String ID	9606.ENSP00000313007
PharmGKB ID	PA32880

Target gene [PABPC1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001898	chr8	267	163		430	View
1003987	chr8	45	49	4	98	View
1004028	chr8	44	48	4	96	View
1004124	chr8	40	49	3	92	View
1004148	chr8	40	48	3	91	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PABPC1 expression and immune infiltrating cell level correlation result in HBV+ samples
PABPC1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).