HIV Target gene Detail Information

> PA2G4 Gene Search Result

Gene Information

Gene Name	PA2G4
Gene ID	5036
Gene Full Name	proliferation-associated 2G4
Gene Alias	EBP1; HG4-1; p38-2G4
Transcripts	ENSG00000170515
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q9UQ80
HGNC ID	HGNC:8550
VEGA ID	OTTHUMG00000170173
OMIM ID	602145
String ID	9606.ENSP00000302886
PharmGKB ID	PA32877

Target gene [PA2G4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002366	chr12	97			97	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PA2G4 expression and immune infiltrating cell level correlation result in HIV+ samples
PA2G4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PA2G4 expression and immune infiltrating cell level correlation result in HIV+ samples
PA2G4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).