HIV Target gene Detail Information

> P2RY8 Gene Search Result

Gene Information

Gene Name	P2RY8
Gene ID	286530
Gene Full Name	P2Y receptor family member 8
Gene Alias	P2Y8
Transcripts	ENSG00000182162
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q86VZ1
HGNC ID	HGNC:15524
VEGA ID	OTTHUMG00000021060
OMIM ID	300525
String ID	9606.ENSP00000370697
Drugbank ID	BE0010035
PharmGKB ID	PA32873

Target gene [P2RY8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4016467	chrY				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of P2RY8 expression and immune infiltrating cell level correlation result in HIV+ samples
P2RY8 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of P2RY8 expression and immune infiltrating cell level correlation result in HIV+ samples
P2RY8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).