HIV Target gene Detail Information

> P2RY6 Gene Search Result

Gene Information

Gene Name	P2RY6
Gene ID	5031
Gene Full Name	pyrimidinergic receptor P2Y6
Gene Alias	P2Y6
Transcripts	ENSG00000171631
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Predicted membrane proteins
Uniport_ID	Q15077
HGNC ID	HGNC:8543
VEGA ID	OTTHUMG00000167969
OMIM ID	602451
String ID	9606.ENSP00000480966
PharmGKB ID	PA32872

Target gene [P2RY6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000144	chr11	765	90	45	900	View
4000156	chr11	734	87	39	860	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of P2RY6 expression and immune infiltrating cell level correlation result in HIV+ samples
P2RY6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).