HBV Target gene Detail Information

> P2RY2 Gene Search Result


Gene Information
Gene Name P2RY2
Gene ID 5029
Gene Full Name purinergic receptor P2Y2
Gene Alias P2U; HP2U; P2U1; P2UR; P2Y2; P2RU1; P2Y2R
Transcripts ENSG00000175591
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters
Uniport_ID P41231
HGNC ID HGNC:8541
VEGA ID OTTHUMG00000167966
OMIM ID 600041
String ID 9606.ENSP00000310305
Drugbank ID BE0002401
PharmGKB ID PA32870
Target gene [P2RY2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1018080 chr11 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of P2RY2 expression and immune infiltrating cell level correlation result in HBV+ samples
P2RY2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).