HIV Target gene Detail Information

> P2RY10 Gene Search Result

Gene Information

Gene Name	P2RY10
Gene ID	27334
Gene Full Name	P2Y receptor family member 10
Gene Alias	P2Y10; LYPSR2
Transcripts	ENSG00000078589
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Predicted membrane proteins
Uniport_ID	O00398
HGNC ID	HGNC:19906
VEGA ID	OTTHUMG00000021896
OMIM ID	300529
String ID	9606.ENSP00000171757
Drugbank ID	BE0010029
PharmGKB ID	PA134873055

Target gene [P2RY10] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011814	chrX	4	2		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of P2RY10 expression and immune infiltrating cell level correlation result in HIV+ samples
P2RY10 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of P2RY10 expression and immune infiltrating cell level correlation result in HIV+ samples
P2RY10 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).