HBV Target gene Detail Information

> P2RX4 Gene Search Result

Gene Information

Gene Name	P2RX4
Gene ID	5025
Gene Full Name	purinergic receptor P2X 4
Gene Alias	P2X4; P2X4R
Transcripts	ENSG00000135124
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q99571
HGNC ID	HGNC:8535
VEGA ID	OTTHUMG00000169155
OMIM ID	600846
String ID	9606.ENSP00000353032
Drugbank ID	BE0005840; BE0005793
PharmGKB ID	PA32864

Target gene [P2RX4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010109	chr12	11	2		13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of P2RX4 expression and immune infiltrating cell level correlation result in HBV+ samples
P2RX4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).