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HPV Target gene Detail Information

> OXTR Gene Search Result


Gene Information
Gene Name OXTR
Gene ID 5021
Gene Full Name oxytocin receptor
Gene Alias OT-R
Transcripts ENSG00000180914
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID P30559
HGNC ID HGNC:8529
VEGA ID OTTHUMG00000090537
OMIM ID 167055
String ID 9606.ENSP00000324270
Drugbank ID BE0000844
PharmGKB ID PA32858
Target gene [OXTR] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5402242 chr3 8 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of OXTR expression and immune infiltrating cell level correlation result in HPV+ samples
OXTR expression: Low -> High

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of OXTR expression and immune infiltrating cell level correlation result in HPV+ samples
OXTR expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of OXTR expression and immune infiltrating cell level correlation result in HPV+ samples
OXTR expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of OXTR expression and immune infiltrating cell level correlation result in HPV+ samples
OXTR expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).