HTLV1 Target gene Detail Information

> OTUD7B Gene Search Result


Gene Information
Gene Name OTUD7B
Gene ID 56957
Gene Full Name OTU deubiquitinase 7B
Gene Alias ZA20D1; CEZANNE
Transcripts ENSG00000264522
Virus HTLV1
Gene Type protein coding
HPA Location Info Microtubules;Cytokinetic bridge;Mitotic spindle;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q6GQQ9
HGNC ID HGNC:16683
VEGA ID OTTHUMG00000012291
OMIM ID 611748
String ID 9606.ENSP00000462729
PharmGKB ID PA134873802
Target gene [OTUD7B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6023186 chr1 4 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of OTUD7B expression and immune infiltrating cell level correlation result in HTLV1+ samples
OTUD7B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).