HIV Target gene Detail Information

> OTUD5 Gene Search Result

Gene Information

Gene Name	OTUD5
Gene ID	55593
Gene Full Name	OTU deubiquitinase 5
Gene Alias	DUBA
Transcripts	ENSG00000068308
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoli fibrillar center;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q96G74
HGNC ID	HGNC:25402
VEGA ID	OTTHUMG00000024130
OMIM ID	300713
String ID	9606.ENSP00000156084
PharmGKB ID	PA142671217

Target gene [OTUD5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001107	chrX	86	41	87	214	View
4001246	chrX	61	49	78	188	View
4001507	chrX	117	25	14	156	View
4009051	chrX	13			13	View
4013066	chrX	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of OTUD5 expression and immune infiltrating cell level correlation result in HIV+ samples
OTUD5 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of OTUD5 expression and immune infiltrating cell level correlation result in HIV+ samples
OTUD5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).