HIV Target gene Detail Information

> OSBPL11 Gene Search Result

Gene Information

Gene Name	OSBPL11
Gene ID	114885
Gene Full Name	oxysterol binding protein like 11
Gene Alias	ORP11; ORP-11; OSBP12; TCCCIA00292
Transcripts	ENSG00000144909
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9BXB4
HGNC ID	HGNC:16397
VEGA ID	OTTHUMG00000159571
OMIM ID	606739
String ID	9606.ENSP00000296220
PharmGKB ID	PA32825

Target gene [OSBPL11] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002760	chr3	48	4	29	81	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of OSBPL11 expression and immune infiltrating cell level correlation result in HIV+ samples
OSBPL11 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of OSBPL11 expression and immune infiltrating cell level correlation result in HIV+ samples
OSBPL11 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).