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HBV Target gene Detail Information

> ORM1 Gene Search Result


Gene Information
Gene Name ORM1
Gene ID 5004
Gene Full Name orosomucoid 1
Gene Alias ORM; AGP1; AGP-A; HEL-S-153w
Transcripts ENSG00000229314
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;Golgi apparatus;Predicted to be secreted;
HPA Protein Class Info Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins
Uniport_ID P02763
HGNC ID HGNC:8498
VEGA ID OTTHUMG00000021012
OMIM ID 138600
String ID 9606.ENSP00000259396
Drugbank ID BE0000925
PharmGKB ID PA260
Target gene [ORM1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006723 chr9 35 35 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ORM1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ORM1 expression: Low -> High
Lollipop of ORM1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ORM1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ORM1 expression and immune infiltrating cell level correlation result in HBV+ samples
ORM1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).