HIV Target gene Detail Information

> ORC4 Gene Search Result

Gene Information

Gene Name	ORC4
Gene ID	5000
Gene Full Name	origin recognition complex subunit 4
Gene Alias	ORC4L; ORC4P
Transcripts	ENSG00000115947
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	O43929
HGNC ID	HGNC:8490
VEGA ID	OTTHUMG00000131849
OMIM ID	603056
String ID	9606.ENSP00000441953
PharmGKB ID	PA32811

Target gene [ORC4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006970	chr2	21			21	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ORC4 expression and immune infiltrating cell level correlation result in HIV+ samples
ORC4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).