HPV Target gene Detail Information

> OR7D4 Gene Search Result

Gene Information

Gene Name	OR7D4
Gene ID	125958
Gene Full Name	olfactory receptor family 7 subfamily D member 4
Gene Alias	OR19B; hg105; OR19-7; OR19-B; OR7D4P
Transcripts	ENSG00000174667
Virus	HPV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Predicted membrane proteins
Uniport_ID	Q8NG98
HGNC ID	HGNC:8380
VEGA ID	OTTHUMG00000179936
OMIM ID	611538
String ID	9606.ENSP00000310488
PharmGKB ID	PA32628

Target gene [OR7D4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5402653	chr19	1	9	5	15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55542 (GEO)	Oropharyngeal squamous cell carcinoma	36	Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO)	Cervical intraepithelial neoplasia	24	Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE55542
HeatMap of cell type fractions in all samples	Lollipop of OR7D4 expression and immune infiltrating cell level correlation result in HPV+ samples
OR7D4 expression: Low -> High

> Dataset: GSE51993
HeatMap of cell type fractions in all samples	Lollipop of OR7D4 expression and immune infiltrating cell level correlation result in HPV+ samples
OR7D4 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of OR7D4 expression and immune infiltrating cell level correlation result in HPV+ samples
OR7D4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).