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HPV Target gene Detail Information

> OR2C1 Gene Search Result


Gene Information
Gene Name OR2C1
Gene ID 4993
Gene Full Name olfactory receptor family 2 subfamily C member 1
Gene Alias OLFmf3; OR2C2P
Transcripts ENSG00000168158
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info G-protein coupled receptors, Predicted membrane proteins
Uniport_ID O95371
HGNC ID HGNC:8242
VEGA ID OTTHUMG00000090505
String ID 9606.ENSP00000307726
PharmGKB ID PA32147
Target gene [OR2C1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5402990 chr16 15 8 23 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of OR2C1 expression and immune infiltrating cell level correlation result in HPV+ samples
OR2C1 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of OR2C1 expression and immune infiltrating cell level correlation result in HPV+ samples
OR2C1 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of OR2C1 expression and immune infiltrating cell level correlation result in HPV+ samples
OR2C1 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of OR2C1 expression and immune infiltrating cell level correlation result in HPV+ samples
OR2C1 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of OR2C1 expression and immune infiltrating cell level correlation result in HPV+ samples
OR2C1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).