HBV Target gene Detail Information

> OPA3 Gene Search Result


Gene Information
Gene Name OPA3
Gene ID 80207
Gene Full Name OPA3, outer mitochondrial membrane lipid metabolism regulator
Gene Alias MGA3
Transcripts ENSG00000125741
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted membrane proteins
Uniport_ID Q9H6K4
HGNC ID HGNC:8142
VEGA ID OTTHUMG00000182125
OMIM ID 606580
String ID 9606.ENSP00000319817
PharmGKB ID PA31929
Target gene [OPA3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1014841 chr19 3 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of OPA3 expression and immune infiltrating cell level correlation result in HBV+ samples
OPA3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).