HBV Target gene Detail Information

> OMA1 Gene Search Result


Gene Information
Gene Name OMA1
Gene ID 115209
Gene Full Name OMA1 zinc metallopeptidase
Gene Alias DAB1; MPRP1; MPRP-1; YKR087C; ZMPOMA1; peptidase; 2010001O09Rik
Transcripts ENSG00000162600
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q96E52
HGNC ID HGNC:29661
VEGA ID OTTHUMG00000010068
OMIM ID 617081
String ID 9606.ENSP00000360270
PharmGKB ID PA134911478
Target gene [OMA1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011867 chr1 2 3 3 8 View
1012336 chr1 2 2 3 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of OMA1 expression and immune infiltrating cell level correlation result in HBV+ samples
OMA1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).