HTLV1 Target gene Detail Information

> OLFML2A Gene Search Result

Gene Information

Gene Name	OLFML2A
Gene ID	169611
Gene Full Name	olfactomedin like 2A
Gene Alias	PRO34319
Transcripts	ENSG00000185585
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Predicted to be secreted;
HPA Protein Class Info	Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q68BL7
HGNC ID	HGNC:27270
VEGA ID	OTTHUMG00000020663
OMIM ID	615899
String ID	9606.ENSP00000362682
PharmGKB ID	PA134967883

Target gene [OLFML2A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003639	chr9	71	65	13	149	View
6019550	chr9	4	4		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of OLFML2A expression and immune infiltrating cell level correlation result in HTLV1+ samples
OLFML2A expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of OLFML2A expression and immune infiltrating cell level correlation result in HTLV1+ samples
OLFML2A expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of OLFML2A expression and immune infiltrating cell level correlation result in HTLV1+ samples
OLFML2A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).