HIV Target gene Detail Information

> OGDH Gene Search Result

Gene Information

Gene Name	OGDH
Gene ID	4967
Gene Full Name	oxoglutarate dehydrogenase
Gene Alias	E1k; OGDC; AKGDH
Transcripts	ENSG00000105953
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q02218
HGNC ID	HGNC:8124
VEGA ID	OTTHUMG00000155304
OMIM ID	613022
String ID	9606.ENSP00000222673
Drugbank ID	BE0000162
PharmGKB ID	PA31910

Target gene [OGDH] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000648	chr7	196	57	80	333	View
4000671	chr7	155	93	75	323	View
4001058	chr7	191	18	14	223	View
4001091	chr7	138	47	31	216	View
4001282	chr7	47	75	61	183	View
4001764	chr7	65	59	10	134	View
4001853	chr7	65	58	4	127	View
4001894	chr7	118	4	2	124	View
4002104	chr7	72	36	4	112	View
4005007	chr7	31	5	1	37	View
4005151	chr7	4	24	7	35	View
4011788	chr7	6			6	View
4014532	chr7	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of OGDH expression and immune infiltrating cell level correlation result in HIV+ samples
OGDH expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of OGDH expression and immune infiltrating cell level correlation result in HIV+ samples
OGDH expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).