HPV Target gene Detail Information

> OFCC1 Gene Search Result


Gene Information
Gene Name OFCC1
Gene ID 266553
Gene Full Name orofacial cleft 1 candidate 1
Gene Alias Opo; MRDS1
Virus HPV
Gene Type protein coding
HGNC ID HGNC:21017
VEGA ID OTTHUMG00000159104
OMIM ID 614287
String ID 9606.ENSP00000419718
PharmGKB ID PA134905750
Target gene [OFCC1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5002245 chr6 12 1 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of OFCC1 expression and immune infiltrating cell level correlation result in HPV+ samples
OFCC1 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of OFCC1 expression and immune infiltrating cell level correlation result in HPV+ samples
OFCC1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).