HBV Target gene Detail Information

> ODF3 Gene Search Result


Gene Information
Gene Name ODF3
Gene ID 113746
Gene Full Name outer dense fiber of sperm tails 3
Gene Alias CT135; TISP50; SHIPPO1
Transcripts ENSG00000177947
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q96PU9
HGNC ID HGNC:19905
VEGA ID OTTHUMG00000119073
OMIM ID 608356
String ID 9606.ENSP00000325868
PharmGKB ID PA134952791
Target gene [ODF3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1402498 chr11 401 227 36 664 View
1402499 chr11 407 278 24 709 View
1402500 chr11 385 219 42 646 View
1403799 chr11 404 268 24 696 View
1403800 chr11 391 217 38 646 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ODF3 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ODF3 expression: Low -> High
Lollipop of ODF3 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ODF3 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ODF3 expression and immune infiltrating cell level correlation result in HBV+ samples
ODF3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).