HBV Target gene Detail Information

> OAZ2 Gene Search Result


Gene Information
Gene Name OAZ2
Gene ID 4947
Gene Full Name ornithine decarboxylase antizyme 2
Gene Alias AZ2
Transcripts ENSG00000180304
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID O95190
HGNC ID HGNC:8096
VEGA ID OTTHUMG00000172473
OMIM ID 604152
String ID 9606.ENSP00000463013
PharmGKB ID PA31885
Target gene [OAZ2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002351 chr15 66 72 151 289 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of OAZ2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
OAZ2 expression: Low -> High
Lollipop of OAZ2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of OAZ2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of OAZ2 expression and immune infiltrating cell level correlation result in HBV+ samples
OAZ2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).