HTLV1 Target gene Detail Information

> NXPH4 Gene Search Result

Gene Information

Gene Name	NXPH4
Gene ID	11247
Gene Full Name	neurexophilin 4
Gene Alias	NPH4
Transcripts	ENSG00000182379
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted secreted proteins
Uniport_ID	O95158
HGNC ID	HGNC:8078
VEGA ID	OTTHUMG00000171241
OMIM ID	604637
String ID	9606.ENSP00000333593
PharmGKB ID	PA31866

Target gene [NXPH4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6006940	chr12	25	14	22	61	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of NXPH4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
NXPH4 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of NXPH4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
NXPH4 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of NXPH4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
NXPH4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).