EBV Target gene Detail Information

> NXF2B Gene Search Result

Gene Information

Gene Name	NXF2B
Gene ID	728343
Gene Full Name	nuclear RNA export factor 2B
Gene Alias	TCP11X2; bA353J17.1
Transcripts	ENSG00000269437
Virus	EBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9GZY0
HGNC ID	HGNC:23984
VEGA ID	OTTHUMG00000154920
String ID	9606.ENSP00000484645
PharmGKB ID	PA162398310

Target gene [NXF2B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
3300187	chrX	2	2		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE102203 (GEO)	B-cell lymphoma	9	Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE45919 (GEO)	Infectious mononucleosis	24	Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO)	Infectious mononucleosis	17	Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO)	Multiple sclerosis	32	Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)

> Dataset: GSE102203
HeatMap of cell type fractions in all samples	Lollipop of NXF2B expression and immune infiltrating cell level correlation result in EBV+ samples
NXF2B expression: Low -> High

> Dataset: GSE45919
HeatMap of cell type fractions in all samples	Lollipop of NXF2B expression and immune infiltrating cell level correlation result in EBV+ samples
NXF2B expression: Low -> High

> Dataset: GSE85599
HeatMap of cell type fractions in all samples	Lollipop of NXF2B expression and immune infiltrating cell level correlation result in EBV+ samples
NXF2B expression: Low -> High

> Dataset: GSE58240
HeatMap of cell type fractions in all samples	Lollipop of NXF2B expression and immune infiltrating cell level correlation result in EBV+ samples
NXF2B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).