HIV Target gene Detail Information

> NUP98 Gene Search Result

Gene Information

Gene Name	NUP98
Gene ID	4928
Gene Full Name	nucleoporin 98
Gene Alias	ADIR2; NUP96; NUP196
Transcripts	ENSG00000110713
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene & Oncogene
Uniport_ID	P52948
HGNC ID	HGNC:8068
VEGA ID	OTTHUMG00000011846
OMIM ID	601021
String ID	9606.ENSP00000316032
PharmGKB ID	PA31856

Target gene [NUP98] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000862	chr11	61	30	176	267	View
4002857	chr11	75	2		77	View
4008595	chr11	12	2		14	View
4008867	chr11	12	1		13	View
4008994	chr11	11	2		13	View
4009205	chr11	12			12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NUP98 expression and immune infiltrating cell level correlation result in HIV+ samples
NUP98 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NUP98 expression and immune infiltrating cell level correlation result in HIV+ samples
NUP98 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).