HIV Target gene Detail Information

> NUP93 Gene Search Result

Gene Information

Gene Name	NUP93
Gene ID	9688
Gene Full Name	nucleoporin 93
Gene Alias	NIC96
Transcripts	ENSG00000102900
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q8N1F7
HGNC ID	HGNC:28958
VEGA ID	OTTHUMG00000133278
OMIM ID	614351
String ID	9606.ENSP00000310668
PharmGKB ID	PA134912759

Target gene [NUP93] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006987	chr16	17	4		21	View
4010471	chr16	7	2		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NUP93 expression and immune infiltrating cell level correlation result in HIV+ samples
NUP93 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NUP93 expression and immune infiltrating cell level correlation result in HIV+ samples
NUP93 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).