HIV Target gene Detail Information

> NUP50 Gene Search Result

Gene Information

Gene Name	NUP50
Gene ID	10762
Gene Full Name	nucleoporin 50
Gene Alias	NPAP60; NPAP60L
Transcripts	ENSG00000093000
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nuclear membrane;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Transporters
Uniport_ID	Q9UKX7
HGNC ID	HGNC:8065
VEGA ID	OTTHUMG00000151265
OMIM ID	604646
String ID	9606.ENSP00000345895
PharmGKB ID	PA31852

Target gene [NUP50] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005790	chr22	28	1		29	View
4006756	chr22	20	3		23	View
4007353	chr22	19	1		20	View
4007923	chr22	17			17	View
4010594	chr22	7	1		8	View
4014451	chr22	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NUP50 expression and immune infiltrating cell level correlation result in HIV+ samples
NUP50 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NUP50 expression and immune infiltrating cell level correlation result in HIV+ samples
NUP50 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).