HIV Target gene Detail Information

> NUMBL Gene Search Result

Gene Information

Gene Name	NUMBL
Gene ID	9253
Gene Full Name	NUMB like, endocytic adaptor protein
Gene Alias	NBL; CAG3A; CTG3a; NUMBR; NUMB-R; TNRC23; NUMBLIKE
Transcripts	ENSG00000105245
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9Y6R0
HGNC ID	HGNC:8061
VEGA ID	OTTHUMG00000182627
OMIM ID	604018
String ID	9606.ENSP00000252891
PharmGKB ID	PA31846

Target gene [NUMBL] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011899	chr19	4	2		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NUMBL expression and immune infiltrating cell level correlation result in HIV+ samples
NUMBL expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).