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HIV Target gene Detail Information

> NUMA1 Gene Search Result


Gene Information
Gene Name NUMA1
Gene ID 4926
Gene Full Name nuclear mitotic apparatus protein 1
Gene Alias NUMA; NMP-22
Transcripts ENSG00000137497
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q14980
HGNC ID HGNC:8059
VEGA ID OTTHUMG00000167697
OMIM ID 164009
String ID 9606.ENSP00000377298
PharmGKB ID PA31844
Target gene [NUMA1] related to VISs
DVIDChromosomeHMTFBSCASum of Overlapped RecordsDetail
4000023 chr11 653 893 881 2427 View
4001206 chr11 111 62 27 200 View
4001501 chr11 29 119 9 157 View
4003559 chr11 52 7 59 View
4003560 chr11 30 24 5 59 View
4003829 chr11 48 6 54 View
4008728 chr11 14 14 View
4009643 chr11 10 1 11 View
4012199 chr11 4 1 5 View
4013260 chr11 4 4 View
Showing 1 to 10 of 10 entries
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Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of NUMA1 expression and immune infiltrating cell level correlation result in HIV+ samples
NUMA1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of NUMA1 expression and immune infiltrating cell level correlation result in HIV+ samples
NUMA1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).