HIV Target gene Detail Information

> NUF2 Gene Search Result

Gene Information

Gene Name	NUF2
Gene ID	83540
Gene Full Name	NDC80 kinetochore complex component NUF2
Gene Alias	CDCA1; CT106; NUF2R
Transcripts	ENSG00000143228
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Kinetochore;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9BZD4
HGNC ID	HGNC:14621
VEGA ID	OTTHUMG00000034275
OMIM ID	611772
String ID	9606.ENSP00000271452
PharmGKB ID	PA162398215

Target gene [NUF2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012846	chr1	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NUF2 expression and immune infiltrating cell level correlation result in HIV+ samples
NUF2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NUF2 expression and immune infiltrating cell level correlation result in HIV+ samples
NUF2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).