HIV Target gene Detail Information

> NUDT3 Gene Search Result

Gene Information

Gene Name	NUDT3
Gene ID	11165
Gene Full Name	nudix hydrolase 3
Gene Alias	DIPP; DIPP1; DIPP-1
Transcripts	ENSG00000272325
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	O95989
HGNC ID	HGNC:8050
VEGA ID	OTTHUMG00000014545
OMIM ID	609228
String ID	9606.ENSP00000476119
PharmGKB ID	PA31834

Target gene [NUDT3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001078	chr6	42	146	31	219	View
4002670	chr6	3	79	3	85	View
4003189	chr6	60	7		67	View
4005923	chr6	28			28	View
4009163	chr6	4	5	3	12	View
4012506	chr6	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NUDT3 expression and immune infiltrating cell level correlation result in HIV+ samples
NUDT3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NUDT3 expression and immune infiltrating cell level correlation result in HIV+ samples
NUDT3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).