HTLV1 Target gene Detail Information

> NUDT2 Gene Search Result


Gene Information
Gene Name NUDT2
Gene ID 318
Gene Full Name nudix hydrolase 2
Gene Alias APAH1
Transcripts ENSG00000164978
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID P50583
HGNC ID HGNC:8049
VEGA ID OTTHUMG00000019817
OMIM ID 602852
String ID 9606.ENSP00000368455
PharmGKB ID PA31833
Target gene [NUDT2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001732 chr9 10 274 73 357 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of NUDT2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
NUDT2 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of NUDT2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
NUDT2 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of NUDT2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
NUDT2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).