HIV Target gene Detail Information

> NUDCD3 Gene Search Result

Gene Information

Gene Name	NUDCD3
Gene ID	23386
Gene Full Name	NudC domain containing 3
Gene Alias	NudCL
Transcripts	ENSG00000015676
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8IVD9
HGNC ID	HGNC:22208
VEGA ID	OTTHUMG00000129174
OMIM ID	610296
String ID	9606.ENSP00000347626
PharmGKB ID	PA134989375

Target gene [NUDCD3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002423	chr7	31	36	28	95	View
4003018	chr7	71	1		72	View
4005191	chr7	9	25	1	35	View
4006708	chr7	18		5	23	View
4007368	chr7	13	6		19	View
4008183	chr7	16			16	View
4010346	chr7	2	6	1	9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NUDCD3 expression and immune infiltrating cell level correlation result in HIV+ samples
NUDCD3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NUDCD3 expression and immune infiltrating cell level correlation result in HIV+ samples
NUDCD3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).