HBV Target gene Detail Information

> NUAK1 Gene Search Result

Gene Information

Gene Name	NUAK1
Gene ID	9891
Gene Full Name	NUAK family kinase 1
Gene Alias	ARK5
Transcripts	ENSG00000074590
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;Microtubules;Nucleoplasm;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	O60285
HGNC ID	HGNC:14311
VEGA ID	OTTHUMG00000169763
OMIM ID	608130
String ID	9606.ENSP00000261402
Drugbank ID	BE0009456
Drug (Cytoscape Annotation)	Sunitinib Malate
PharmGKB ID	PA142671242

Target gene [NUAK1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003023	chr12	137	31	6	174	View
1006921	chr12	4	10	18	32	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NUAK1 expression and immune infiltrating cell level correlation result in HBV+ samples
NUAK1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).