HIV Target gene Detail Information

> NTRK1 Gene Search Result

Gene Information

Gene Name	NTRK1
Gene ID	4914
Gene Full Name	neurotrophic receptor tyrosine kinase 1
Gene Alias	MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
Transcripts	ENSG00000198400
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins
Gene Function	Oncogene
Uniport_ID	P04629
HGNC ID	HGNC:8031
VEGA ID	OTTHUMG00000041304
OMIM ID	191315
String ID	9606.ENSP00000431418
Drugbank ID	BE0001039
PharmGKB ID	PA31817

Target gene [NTRK1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4014305	chr1		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NTRK1 expression and immune infiltrating cell level correlation result in HIV+ samples
NTRK1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).