HBV Target gene Detail Information

> NTN4 Gene Search Result

Gene Information

Gene Name	NTN4
Gene ID	59277
Gene Full Name	netrin 4
Gene Alias	PRO3091
Transcripts	ENSG00000074527
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q9HB63
HGNC ID	HGNC:13658
VEGA ID	OTTHUMG00000170290
OMIM ID	610401
String ID	9606.ENSP00000340998
PharmGKB ID	PA31815

Target gene [NTN4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008468	chr3	18	2		20	View
1011260	chr3	7	2		9	View
1015405	chr3	2			2	View
1015551	chr3	2			2	View
1015727	chr3	2			2	View
1019321	chr12				0	View
1402461	chr3	18	2		20	View
1403926	chr3	7	2		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NTN4 expression and immune infiltrating cell level correlation result in HBV+ samples
NTN4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).