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HBV Target gene Detail Information

> NTN1 Gene Search Result


Gene Information
Gene Name NTN1
Gene ID 9423
Gene Full Name netrin 1
Gene Alias NTN1L
Transcripts ENSG00000065320
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID O95631
HGNC ID HGNC:8029
VEGA ID OTTHUMG00000130257
OMIM ID 601614
String ID 9606.ENSP00000173229
PharmGKB ID PA31813
Target gene [NTN1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002850 chr17 198 198 View
1010580 chr17 11 11 View
1400133 chr12 5 2 7 View
1401117 chr17 198 198 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of NTN1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
NTN1 expression: Low -> High
Lollipop of NTN1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of NTN1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of NTN1 expression and immune infiltrating cell level correlation result in HBV+ samples
NTN1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).