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HIV Target gene Detail Information

> NT5C2 Gene Search Result


Gene Information
Gene Name NT5C2
Gene ID 22978
Gene Full Name 5'-nucleotidase, cytosolic II
Gene Alias GMP; NT5B; PNT5; SPG45; SPG65; cN-II
Transcripts ENSG00000076685
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID P49902
HGNC ID HGNC:8022
VEGA ID OTTHUMG00000018981
OMIM ID 600417
String ID 9606.ENSP00000339479
Drugbank ID BE0000261
PharmGKB ID PA31801
Target gene [NT5C2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001243 chr10 4 119 65 188 View
4001930 chr10 90 17 15 122 View
4013560 chr10 1 2 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of NT5C2 expression and immune infiltrating cell level correlation result in HIV+ samples
NT5C2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of NT5C2 expression and immune infiltrating cell level correlation result in HIV+ samples
NT5C2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).