HIV Target gene Detail Information

> NSUN2 Gene Search Result


Gene Information
Gene Name NSUN2
Gene ID 54888
Gene Full Name NOP2/Sun RNA methyltransferase family member 2
Gene Alias MISU; MRT5; SAKI; TRM4
Transcripts ENSG00000037474
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q08J23
HGNC ID HGNC:25994
VEGA ID OTTHUMG00000090455
OMIM ID 610916
String ID 9606.ENSP00000264670
PharmGKB ID PA134953940
Target gene [NSUN2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002652 chr5 70 14 1 85 View
4009057 chr5 3 8 2 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of NSUN2 expression and immune infiltrating cell level correlation result in HIV+ samples
NSUN2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of NSUN2 expression and immune infiltrating cell level correlation result in HIV+ samples
NSUN2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).